A Comparison of Four Treatments for Generalized Convulsive Status Epilepticus

A comparison of four treatments for generalized convulsive status epilepticus. Veterans Affairs Status Epilepticus Cooperative Study Group.

BACKGROUND AND METHODS Although generalized convulsive status epilepticus is a life-threatening emergency, the best initial drug treatment is uncertain. We conducted a five-year randomized, double-blind, multicenter trial of four intravenous regimens: diazepam (0.15 mg per kilogram of body weight) followed by phenytoin (18 mg per kilogram), lorazepam (0.1 mg per kilogram), phenobarbital (15 mg ...

Common Reference-based Indirect Comparison Meta-analysis of Intravenous Valproate versus Intravenous Phenobarbitone in Generalized Convulsive Status Epilepticus Protocol

Efficacy of continuous midazolam infusion and mortality in childhood refractory generalized convulsive status epilepticus

PURPOSE Continuous midazolam infusion is commonly used for the management of status epilepticus (SE). The purpose of this study was to assess the efficacy of midazolam and mortality in childhood refractory generalized convulsive SE. METHODS We included 27 children with refractory generalized convulsive SE. Midazolam was given 0.2 mg/kg as bolus, followed by 1-5 microg/kg/min as continuous inf...

Iv Lidocaine: a Second Line Drug Therapy for Pediatric Convulsive Status Epilepticus?

R. Fallah MD Abstract: Objective Refractory convulsive Status Epilepticus (SE) which does not respond to first line drugs (benzodiazepines, phenytoin and phenobarbital) heralds an emergency condition in pediatric neurology which can cause irreparable brain damage. There is no consensus on the choice of drug treatment for refractory generalized convulsive status epilepticus in children. Lidocain...

Non-convulsive status epilepticus in elderly individuals: report of four representative cases.

OBJECTIVE the purpose of this article is to describe the clinical and electroencephalographic features of four elderly patients diagnosed as having non-convulsive status epilepticus. METHODS four females ranging in age from 74 to 81 years were admitted to our hospital because of confusion and altered mental state. We recognised four distinctive entities: i) Absence status in a patient with pr...